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Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism
The host cell protein tetherin can restrict the release of enveloped viruses from infected cells. The HIV-1 protein Vpu counteracts tetherin by removing it from the site of viral budding, the plasma membrane, and this process depends on specific interactions between the transmembrane domains of Vpu...
Autores principales: | Gnirß, Kerstin, Fiedler, Marie, Krämer-Kühl, Annika, Bolduan, Sebastian, Mittler, Eva, Becker, Stephan, Schindler, Michael, Pöhlmann, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014715/ https://www.ncbi.nlm.nih.gov/pubmed/24721789 http://dx.doi.org/10.3390/v6041654 |
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