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A screen for hydroxymethylcytosine and formylcytosine binding proteins suggests functions in transcription and chromatin regulation

BACKGROUND: DNA methylation (5mC) plays important roles in epigenetic regulation of genome function. Recently, TET hydroxylases have been found to oxidise 5mC to hydroxymethylcytosine (5hmC), formylcytosine (5fC) and carboxylcytosine (5caC) in DNA. These derivatives have a role in demethylation of D...

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Detalles Bibliográficos
Autores principales:	Iurlaro, Mario, Ficz, Gabriella, Oxley, David, Raiber, Eun-Ang, Bachman, Martin, Booth, Michael J, Andrews, Simon, Balasubramanian, Shankar, Reik, Wolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014808/ https://www.ncbi.nlm.nih.gov/pubmed/24156278 http://dx.doi.org/10.1186/gb-2013-14-10-r119

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