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Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways
Nitro-oleic acid (OA-NO2), acting as anti-inflammatory signaling mediators, are involved in multiple signaling pathways. Lipoprotein-associated phospholipase A2 (Lp-PLA2) is well known as a cardiovascular risk biomarker. Our results showed that OA-NO2 downregulated the expression of Lp-PLA2 in a tim...
Autores principales: | Wang, Gangqi, Ji, Yuan, Li, Zhuang, Han, Xiaolei, Guo, Nannan, Song, Qi, Quan, Longquan, Wang, Tiedong, Han, Wenyu, Pang, Daxin, Ouyang, Hongsheng, Tang, Xiaochun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014883/ https://www.ncbi.nlm.nih.gov/pubmed/24809325 http://dx.doi.org/10.1038/srep04905 |
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