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Augmented reduction of islet β‐cell mass in Goto‐Kakizaki rats fed high‐fat diet and its suppression by pitavastatin treatment
Aims/Introduction: High fat diet (HFD) is known to be a risk for development of type 2 diabetes. It is unclear, however, how it affects the glucose tolerance or the islet structure in type 2 diabetes. The aim of this study is: (i) to examine the effects of HFD on the islet in GK rats, non‐obese typ...
Autores principales: | Mizukami, Hiroki, Inaba, Wataru, Takahashi, Kazunori, Inoue, Keisuke, Sawanobori, Kimio, Yagihashi, Soroku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014944/ https://www.ncbi.nlm.nih.gov/pubmed/24843571 http://dx.doi.org/10.1111/j.2040-1124.2011.00173.x |
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