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Augmented reduction of islet β‐cell mass in Goto‐Kakizaki rats fed high‐fat diet and its suppression by pitavastatin treatment

Aims/Introduction:  High fat diet (HFD) is known to be a risk for development of type 2 diabetes. It is unclear, however, how it affects the glucose tolerance or the islet structure in type 2 diabetes. The aim of this study is: (i) to examine the effects of HFD on the islet in GK rats, non‐obese typ...

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Detalles Bibliográficos
Autores principales: Mizukami, Hiroki, Inaba, Wataru, Takahashi, Kazunori, Inoue, Keisuke, Sawanobori, Kimio, Yagihashi, Soroku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014944/
https://www.ncbi.nlm.nih.gov/pubmed/24843571
http://dx.doi.org/10.1111/j.2040-1124.2011.00173.x

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