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Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes

Pregnancy and the postpartum period are associated with changes of the immune system. These changes might eventually result in autoimmune diseases, such as Graves’ disease and type 1 diabetes mellitus, in the postpartum period. We describe a case of a patient with gestational diabetes who developed...

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Autores principales: Negishi, Mayumi, Shimomura, Kenju, Proks, Peter, Nakahara, Rieko, Murakami, Masami, Shimomura, Yohnosuke, Kobayashi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014976/
https://www.ncbi.nlm.nih.gov/pubmed/24843507
http://dx.doi.org/10.1111/j.2040-1124.2010.00089.x
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author Negishi, Mayumi
Shimomura, Kenju
Proks, Peter
Nakahara, Rieko
Murakami, Masami
Shimomura, Yohnosuke
Kobayashi, Isao
author_facet Negishi, Mayumi
Shimomura, Kenju
Proks, Peter
Nakahara, Rieko
Murakami, Masami
Shimomura, Yohnosuke
Kobayashi, Isao
author_sort Negishi, Mayumi
collection PubMed
description Pregnancy and the postpartum period are associated with changes of the immune system. These changes might eventually result in autoimmune diseases, such as Graves’ disease and type 1 diabetes mellitus, in the postpartum period. We describe a case of a patient with gestational diabetes who developed both Graves’ disease and type 1 diabetes mellitus in the postpartum period. The pathology of gestational diabetes (GDM) is close to that of type 2 diabetes mellitus. However, the present case emphasizes the importance of screening and monitoring high‐risk GDM patients for all available autoimmune antibodies throughout pregnancy and the postpartum period, as GDM has a risk of developing into type 1 diabetes and multiple autoimmune diseases. In addition, only Graves’ disease was transient, whereas type 1 diabetes mellitus remained permanent in the present case. Thus, the present case shows etiological differences between these two autoimmune diseases. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2010.00089.x,2011)
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spelling pubmed-40149762014-05-19 Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes Negishi, Mayumi Shimomura, Kenju Proks, Peter Nakahara, Rieko Murakami, Masami Shimomura, Yohnosuke Kobayashi, Isao J Diabetes Investig Articles Pregnancy and the postpartum period are associated with changes of the immune system. These changes might eventually result in autoimmune diseases, such as Graves’ disease and type 1 diabetes mellitus, in the postpartum period. We describe a case of a patient with gestational diabetes who developed both Graves’ disease and type 1 diabetes mellitus in the postpartum period. The pathology of gestational diabetes (GDM) is close to that of type 2 diabetes mellitus. However, the present case emphasizes the importance of screening and monitoring high‐risk GDM patients for all available autoimmune antibodies throughout pregnancy and the postpartum period, as GDM has a risk of developing into type 1 diabetes and multiple autoimmune diseases. In addition, only Graves’ disease was transient, whereas type 1 diabetes mellitus remained permanent in the present case. Thus, the present case shows etiological differences between these two autoimmune diseases. (J Diabetes Invest, doi: 10.1111/j.2040‐1124.2010.00089.x,2011) Blackwell Publishing Ltd 2011-08-02 2010-12-27 /pmc/articles/PMC4014976/ /pubmed/24843507 http://dx.doi.org/10.1111/j.2040-1124.2010.00089.x Text en © 2010 Asian Association for the Study of Diabetes and Blackwell Publishing Asia Pty Ltd
spellingShingle Articles
Negishi, Mayumi
Shimomura, Kenju
Proks, Peter
Nakahara, Rieko
Murakami, Masami
Shimomura, Yohnosuke
Kobayashi, Isao
Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
title Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
title_full Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
title_fullStr Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
title_full_unstemmed Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
title_short Development of postpartum Graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
title_sort development of postpartum graves’ disease and type 1 diabetes after delivery in a patient with gestational diabetes
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014976/
https://www.ncbi.nlm.nih.gov/pubmed/24843507
http://dx.doi.org/10.1111/j.2040-1124.2010.00089.x
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