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Arg(972) Insulin receptor substrate-1 is associated with decreased serum angiotensin-converting enzyme 2 levels in acute myocardial infarction patients: in vivo and in vitro evidence

BACKGROUND: Activation of the renin-angiotensin system (RAS) plays a critical role in the pathophysiology of myocardial infarction (MI) and the development of heart failure. Both angiotensin-converting enzyme 2 (ACE2) and insulin/insulin receptor substrate-1 (IRS-1) show cardioprotective effects aft...

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Detalles Bibliográficos
Autores principales:	Liu, Wei, Zhou, Xinmin, Yu, Fenglei, Hu, Jianguo, Hu, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015180/ https://www.ncbi.nlm.nih.gov/pubmed/24134599 http://dx.doi.org/10.1186/1475-2840-12-151

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