Optimized Lentiviral Vectors for HIV Gene Therapy: Multiplexed Expression of Small RNAs and Inclusion of MGMT(P140K) Drug Resistance Gene

Gene therapy with hematopoietic stem and progenitor cells is a promising approach to engineering immunity to human immunodeficiency virus (HIV) that may lead to a functional cure for acquired immunodeficiency syndrome (AIDS). In support of this approach, we created lentiviral vectors with an enginee...

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Detalles Bibliográficos
Autores principales: Chung, Janet, Scherer, Lisa J, Gu, Angel, Gardner, Agnes M, Torres-Coronado, Monica, Epps, Elizabeth W, DiGiusto, David L, Rossi, John J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015224/
https://www.ncbi.nlm.nih.gov/pubmed/24576853
http://dx.doi.org/10.1038/mt.2014.32

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