Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome

BACKGROUND: Phage-encoded serine integrases, such as φC31 integrase, are widely used for genome engineering. Fifteen such integrases have been described but their utility for genome engineering has not been compared in uniform assays. RESULTS: We have compared fifteen serine integrases for their uti...

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Detalles Bibliográficos
Autores principales: Xu, Zhengyao, Thomas, Louise, Davies, Ben, Chalmers, Ronald, Smith, Maggie, Brown, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015280/
https://www.ncbi.nlm.nih.gov/pubmed/24139482
http://dx.doi.org/10.1186/1472-6750-13-87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015280/
https://www.ncbi.nlm.nih.gov/pubmed/24139482
http://dx.doi.org/10.1186/1472-6750-13-87

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