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CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53

The multifunctional CCCTC-binding factor (CTCF) protein exhibits a broad range of functions, including that of insulator and higher-order chromatin organizer. We found that CTCF comprises a previously unrecognized region that is necessary and sufficient to bind RNA (RNA-binding region [RBR]) and is...

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Detalles Bibliográficos
Autores principales:	Saldaña-Meyer, Ricardo, González-Buendía, Edgar, Guerrero, Georgina, Narendra, Varun, Bonasio, Roberto, Recillas-Targa, Félix, Reinberg, Danny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015496/ https://www.ncbi.nlm.nih.gov/pubmed/24696455 http://dx.doi.org/10.1101/gad.236869.113

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