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Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice

BACKGROUND: The next big challenge in human genetics is understanding the 98% of the genome that comprises non-coding DNA. Hidden in this DNA are sequences critical for gene regulation, and new experimental strategies are needed to understand the functional role of gene-regulation sequences in healt...

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Detalles Bibliográficos
Autores principales:	Schmouth, Jean-François, Castellarin, Mauro, Laprise, Stéphanie, Banks, Kathleen G, Bonaguro, Russell J, McInerny, Simone C, Borretta, Lisa, Amirabbasi, Mahsa, Korecki, Andrea J, Portales-Casamar, Elodie, Wilson, Gary, Dreolini, Lisa, Jones, Steven JM, Wasserman, Wyeth W, Goldowitz, Daniel, Holt, Robert A, Simpson, Elizabeth M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015596/ https://www.ncbi.nlm.nih.gov/pubmed/24124870 http://dx.doi.org/10.1186/1741-7007-11-106

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