Cargando…
FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases
BACKGROUND: Bleomycin has become an integral part of chemotherapy in patients with germ-cell tumors. One of the most feared side effects is bleomycin-induced pneumonitis. In patients with mild or moderate BIP, radiological signs disappear almost completely within nine months after discontinuation of...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015643/ https://www.ncbi.nlm.nih.gov/pubmed/24148527 http://dx.doi.org/10.1186/1471-2407-13-491 |
_version_ | 1782315369061416960 |
---|---|
author | De Vos, Filip YFL Mulder, Sasja F Drenth, Joost PH Nagtegaal, Iris D Fütterer, Jurgen J van der Graaf, Winette TA |
author_facet | De Vos, Filip YFL Mulder, Sasja F Drenth, Joost PH Nagtegaal, Iris D Fütterer, Jurgen J van der Graaf, Winette TA |
author_sort | De Vos, Filip YFL |
collection | PubMed |
description | BACKGROUND: Bleomycin has become an integral part of chemotherapy in patients with germ-cell tumors. One of the most feared side effects is bleomycin-induced pneumonitis. In patients with mild or moderate BIP, radiological signs disappear almost completely within nine months after discontinuation of bleomycin treatment. CASE PRESENTATION: We present a patient with a history of non seminoma of the testis and bleomycin-induced pneumonitis. During follow-up, regression of the hypothesis of eosinophilic migration to the liver after regression of bleomycin-induced pneumonitis is highly suspicious based on transient eosinophilia and focal eosinophilic liver disease. CONCLUSION: As follow up may consist of CT scanning in germ-line tumor patients, transient eosinophilic liver lesions reported during regressive bleomycin-induced pneumonitis should not be presumed automatically as metastatic tumor relapse and require further sequential imaging and pathological examination. |
format | Online Article Text |
id | pubmed-4015643 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40156432014-05-10 FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases De Vos, Filip YFL Mulder, Sasja F Drenth, Joost PH Nagtegaal, Iris D Fütterer, Jurgen J van der Graaf, Winette TA BMC Cancer Case Report BACKGROUND: Bleomycin has become an integral part of chemotherapy in patients with germ-cell tumors. One of the most feared side effects is bleomycin-induced pneumonitis. In patients with mild or moderate BIP, radiological signs disappear almost completely within nine months after discontinuation of bleomycin treatment. CASE PRESENTATION: We present a patient with a history of non seminoma of the testis and bleomycin-induced pneumonitis. During follow-up, regression of the hypothesis of eosinophilic migration to the liver after regression of bleomycin-induced pneumonitis is highly suspicious based on transient eosinophilia and focal eosinophilic liver disease. CONCLUSION: As follow up may consist of CT scanning in germ-line tumor patients, transient eosinophilic liver lesions reported during regressive bleomycin-induced pneumonitis should not be presumed automatically as metastatic tumor relapse and require further sequential imaging and pathological examination. BioMed Central 2013-10-22 /pmc/articles/PMC4015643/ /pubmed/24148527 http://dx.doi.org/10.1186/1471-2407-13-491 Text en Copyright © 2013 De Vos et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report De Vos, Filip YFL Mulder, Sasja F Drenth, Joost PH Nagtegaal, Iris D Fütterer, Jurgen J van der Graaf, Winette TA FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
title | FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
title_full | FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
title_fullStr | FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
title_full_unstemmed | FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
title_short | FELD better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
title_sort | feld better not thinking of metastases only when liver lesions appear after bleomycin-based treatment for non-seminoma testis from metastases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015643/ https://www.ncbi.nlm.nih.gov/pubmed/24148527 http://dx.doi.org/10.1186/1471-2407-13-491 |
work_keys_str_mv | AT devosfilipyfl feldbetternotthinkingofmetastasesonlywhenliverlesionsappearafterbleomycinbasedtreatmentfornonseminomatestisfrommetastases AT muldersasjaf feldbetternotthinkingofmetastasesonlywhenliverlesionsappearafterbleomycinbasedtreatmentfornonseminomatestisfrommetastases AT drenthjoostph feldbetternotthinkingofmetastasesonlywhenliverlesionsappearafterbleomycinbasedtreatmentfornonseminomatestisfrommetastases AT nagtegaalirisd feldbetternotthinkingofmetastasesonlywhenliverlesionsappearafterbleomycinbasedtreatmentfornonseminomatestisfrommetastases AT futtererjurgenj feldbetternotthinkingofmetastasesonlywhenliverlesionsappearafterbleomycinbasedtreatmentfornonseminomatestisfrommetastases AT vandergraafwinetteta feldbetternotthinkingofmetastasesonlywhenliverlesionsappearafterbleomycinbasedtreatmentfornonseminomatestisfrommetastases |