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Direct non-productive HIV-1 infection in a T-cell line is driven by cellular activation state and NFκB

BACKGROUND: Molecular latency allows HIV-1 to persist in resting memory CD4+ T-cells as transcriptionally silent provirus integrated into host chromosomal DNA. Multiple transcriptional regulatory mechanisms for HIV-1 latency have been described in the context of progressive epigenetic silencing and...

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Detalles Bibliográficos
Autores principales:	Dahabieh, Matthew S, Ooms, Marcel, Brumme, Chanson, Taylor, Jeremy, Harrigan, P Richard, Simon, Viviana, Sadowski, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015675/ https://www.ncbi.nlm.nih.gov/pubmed/24502247 http://dx.doi.org/10.1186/1742-4690-11-17

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