Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells

Autophagy1 is a complex of adaptive cellular response that enhances cancer cell survival in the face of cellular stresses such as chemothery. Here we show that in human gallbladder carcinoma (GBC) cells lines, SGC-996 and GBC-SD, autophagy is induced by the DNA damaging agent 5-fluorouracil (5-FU)....

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Xiao, Tang, JiaCheng, Liang, YueLong, Jin, RenAn, Cai, XiuJun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015784/
https://www.ncbi.nlm.nih.gov/pubmed/24581180
http://dx.doi.org/10.1186/2045-3701-4-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015784/
https://www.ncbi.nlm.nih.gov/pubmed/24581180
http://dx.doi.org/10.1186/2045-3701-4-10

Ejemplares similares