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Differential sensitivity to the acute and sensitizing behavioral effects of methylphenidate as a function of strain in adolescent and young adult rats

BACKGROUND: Behavioral effects of stimulant drugs are influenced by non-pharmacological factors, including genetic variability and age. We examined acute and sensitized locomotor effects of methylphenidate in adolescent and early adult male Sprague Dawley (SD), spontaneously hypertensive (SHR) and W...

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Detalles Bibliográficos
Autores principales: Yetnikoff, Leora, Arvanitogiannis, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015822/
https://www.ncbi.nlm.nih.gov/pubmed/24134881
http://dx.doi.org/10.1186/1744-9081-9-38