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Evolution of Tertiary Structure of Viral RNA Dependent Polymerases
Viral RNA dependent polymerases (vRdPs) are present in all RNA viruses; unfortunately, their sequence similarity is too low for phylogenetic studies. Nevertheless, vRdP protein structures are remarkably conserved. In this study, we used the structural similarity of vRdPs to reconstruct their evoluti...
Autores principales: | Černý, Jiří, Černá Bolfíková, Barbora, Valdés, James J., Grubhoffer, Libor, Růžek, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015915/ https://www.ncbi.nlm.nih.gov/pubmed/24816789 http://dx.doi.org/10.1371/journal.pone.0096070 |
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