MLV requires Tap/NXF1-dependent pathway to export its unspliced RNA to the cytoplasm and to express both spliced and unspliced RNAs

BACKGROUND: Eukaryotic cells have evolved stringent proofreading mechanisms to ensure that intron-containing mRNAs do not leave the nucleus. However, all retroviruses must bypass this checkpoint for replication. Indeed, their primary polycistronic transcript (Full-Length) must reach the cytoplasm to...

Descripción completa

Detalles Bibliográficos
Autores principales: Pessel-Vivares, Lucie, Ferrer, Mireia, Lainé, Sébastien, Mougel, Marylène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015919/
https://www.ncbi.nlm.nih.gov/pubmed/24597485
http://dx.doi.org/10.1186/1742-4690-11-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015919/
https://www.ncbi.nlm.nih.gov/pubmed/24597485
http://dx.doi.org/10.1186/1742-4690-11-21

Ejemplares similares