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Transcriptional regulation prediction of antiestrogen resistance in breast cancer based on RNA polymerase II binding data

BACKGROUND: Although endocrine therapy impedes estrogen-ER signaling pathway and thus reduces breast cancer mortality, patients remain at continued risk of relapse after tamoxifen or other endocrine therapies. Understanding the mechanisms of endocrine resistance, particularly the role of transcripti...

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Detalles Bibliográficos
Autores principales: Zhang, Denan, Wang, Guohua, Wang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015922/
https://www.ncbi.nlm.nih.gov/pubmed/24564526
http://dx.doi.org/10.1186/1471-2105-15-S2-S10