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Transcriptional regulation prediction of antiestrogen resistance in breast cancer based on RNA polymerase II binding data
BACKGROUND: Although endocrine therapy impedes estrogen-ER signaling pathway and thus reduces breast cancer mortality, patients remain at continued risk of relapse after tamoxifen or other endocrine therapies. Understanding the mechanisms of endocrine resistance, particularly the role of transcripti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015922/ https://www.ncbi.nlm.nih.gov/pubmed/24564526 http://dx.doi.org/10.1186/1471-2105-15-S2-S10 |