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Semapimod Sensitizes Glioblastoma Tumors to Ionizing Radiation by Targeting Microglia
Glioblastoma is the most malignant and lethal form of astrocytoma, with patients having a median survival time of approximately 15 months with current therapeutic modalities. It is therefore important to identify novel therapeutics. There is mounting evidence that microglia (specialized brain-reside...
Autores principales: | Miller, Ian S., Didier, Sebastien, Murray, David W., Turner, Tia H., Issaivanan, Magimairajan, Ruggieri, Rosamaria, Al-Abed, Yousef, Symons, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015930/ https://www.ncbi.nlm.nih.gov/pubmed/24816734 http://dx.doi.org/10.1371/journal.pone.0095885 |
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