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Semapimod Sensitizes Glioblastoma Tumors to Ionizing Radiation by Targeting Microglia

Glioblastoma is the most malignant and lethal form of astrocytoma, with patients having a median survival time of approximately 15 months with current therapeutic modalities. It is therefore important to identify novel therapeutics. There is mounting evidence that microglia (specialized brain-reside...

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Detalles Bibliográficos
Autores principales: Miller, Ian S., Didier, Sebastien, Murray, David W., Turner, Tia H., Issaivanan, Magimairajan, Ruggieri, Rosamaria, Al-Abed, Yousef, Symons, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015930/
https://www.ncbi.nlm.nih.gov/pubmed/24816734
http://dx.doi.org/10.1371/journal.pone.0095885

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