Analysis of the Effects of Five Factors Relevant to In Vitro Chondrogenesis of Human Mesenchymal Stem Cells Using Factorial Design and High Throughput mRNA-Profiling

The in vitro process of chondrogenic differentiation of mesenchymal stem cells for tissue engineering has been shown to require three-dimensional culture along with the addition of differentiation factors to the culture medium. In general, this leads to a phenotype lacking some of the cardinal featu...

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Detalles Bibliográficos
Autores principales: Jakobsen, Rune B., Østrup, Esben, Zhang, Xiaolan, Mikkelsen, Tarjei S., Brinchmann, Jan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015996/
https://www.ncbi.nlm.nih.gov/pubmed/24816923
http://dx.doi.org/10.1371/journal.pone.0096615

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