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Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study
AIM: To study the pattern and prevalence of dyslipidemia in a large representative sample of four selected regions in India. METHODS: Phase I of the Indian Council of Medical Research–India Diabetes (ICMR-INDIAB) study was conducted in a representative population of three states of India [Tamil Nadu...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016101/ https://www.ncbi.nlm.nih.gov/pubmed/24817067 http://dx.doi.org/10.1371/journal.pone.0096808 |
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author | Joshi, Shashank R. Anjana, Ranjit Mohan Deepa, Mohan Pradeepa, Rajendra Bhansali, Anil Dhandania, Vinay K. Joshi, Prashant P. Unnikrishnan, Ranjit Nirmal, Elangovan Subashini, Radhakrishnan Madhu, Sri Venkata Rao, Paturi Vishnupriya Das, Ashok Kumar Kaur, Tanvir Shukla, Deepak Kumar Mohan, Viswanathan |
author_facet | Joshi, Shashank R. Anjana, Ranjit Mohan Deepa, Mohan Pradeepa, Rajendra Bhansali, Anil Dhandania, Vinay K. Joshi, Prashant P. Unnikrishnan, Ranjit Nirmal, Elangovan Subashini, Radhakrishnan Madhu, Sri Venkata Rao, Paturi Vishnupriya Das, Ashok Kumar Kaur, Tanvir Shukla, Deepak Kumar Mohan, Viswanathan |
author_sort | Joshi, Shashank R. |
collection | PubMed |
description | AIM: To study the pattern and prevalence of dyslipidemia in a large representative sample of four selected regions in India. METHODS: Phase I of the Indian Council of Medical Research–India Diabetes (ICMR-INDIAB) study was conducted in a representative population of three states of India [Tamil Nadu, Maharashtra and Jharkhand] and one Union Territory [Chandigarh], and covered a population of 213 million people using stratified multistage sampling design to recruit individuals ≥20 years of age. All the study subjects (n = 16,607) underwent anthropometric measurements and oral glucose tolerance tests were done using capillary blood (except in self-reported diabetes). In addition, in every 5th subject (n = 2042), a fasting venous sample was collected and assayed for lipids. Dyslipidemia was diagnosed using National Cholesterol Education Programme (NCEP) guidelines. RESULTS: Of the subjects studied, 13.9% had hypercholesterolemia, 29.5% had hypertriglyceridemia, 72.3% had low HDL-C, 11.8% had high LDL-C levels and 79% had abnormalities in one of the lipid parameters. Regional disparity exists with the highest rates of hypercholesterolemia observed in Tamilnadu (18.3%), highest rates of hypertriglyceridemia in Chandigarh (38.6%), highest rates of low HDL-C in Jharkhand (76.8%) and highest rates of high LDL-C in Tamilnadu (15.8%). Except for low HDL-C and in the state of Maharashtra, in all other states, urban residents had the highest prevalence of lipid abnormalities compared to rural residents. Low HDL-C was the most common lipid abnormality (72.3%) in all the four regions studied; in 44.9% of subjects, it was present as an isolated abnormality. Common significant risk factors for dyslipidemia included obesity, diabetes, and dysglycemia. CONCLUSION: The prevalence of dyslipidemia is very high in India, which calls for urgent lifestyle intervention strategies to prevent and manage this important cardiovascular risk factor. |
format | Online Article Text |
id | pubmed-4016101 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-40161012014-05-14 Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study Joshi, Shashank R. Anjana, Ranjit Mohan Deepa, Mohan Pradeepa, Rajendra Bhansali, Anil Dhandania, Vinay K. Joshi, Prashant P. Unnikrishnan, Ranjit Nirmal, Elangovan Subashini, Radhakrishnan Madhu, Sri Venkata Rao, Paturi Vishnupriya Das, Ashok Kumar Kaur, Tanvir Shukla, Deepak Kumar Mohan, Viswanathan PLoS One Research Article AIM: To study the pattern and prevalence of dyslipidemia in a large representative sample of four selected regions in India. METHODS: Phase I of the Indian Council of Medical Research–India Diabetes (ICMR-INDIAB) study was conducted in a representative population of three states of India [Tamil Nadu, Maharashtra and Jharkhand] and one Union Territory [Chandigarh], and covered a population of 213 million people using stratified multistage sampling design to recruit individuals ≥20 years of age. All the study subjects (n = 16,607) underwent anthropometric measurements and oral glucose tolerance tests were done using capillary blood (except in self-reported diabetes). In addition, in every 5th subject (n = 2042), a fasting venous sample was collected and assayed for lipids. Dyslipidemia was diagnosed using National Cholesterol Education Programme (NCEP) guidelines. RESULTS: Of the subjects studied, 13.9% had hypercholesterolemia, 29.5% had hypertriglyceridemia, 72.3% had low HDL-C, 11.8% had high LDL-C levels and 79% had abnormalities in one of the lipid parameters. Regional disparity exists with the highest rates of hypercholesterolemia observed in Tamilnadu (18.3%), highest rates of hypertriglyceridemia in Chandigarh (38.6%), highest rates of low HDL-C in Jharkhand (76.8%) and highest rates of high LDL-C in Tamilnadu (15.8%). Except for low HDL-C and in the state of Maharashtra, in all other states, urban residents had the highest prevalence of lipid abnormalities compared to rural residents. Low HDL-C was the most common lipid abnormality (72.3%) in all the four regions studied; in 44.9% of subjects, it was present as an isolated abnormality. Common significant risk factors for dyslipidemia included obesity, diabetes, and dysglycemia. CONCLUSION: The prevalence of dyslipidemia is very high in India, which calls for urgent lifestyle intervention strategies to prevent and manage this important cardiovascular risk factor. Public Library of Science 2014-05-09 /pmc/articles/PMC4016101/ /pubmed/24817067 http://dx.doi.org/10.1371/journal.pone.0096808 Text en © 2014 Joshi et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Joshi, Shashank R. Anjana, Ranjit Mohan Deepa, Mohan Pradeepa, Rajendra Bhansali, Anil Dhandania, Vinay K. Joshi, Prashant P. Unnikrishnan, Ranjit Nirmal, Elangovan Subashini, Radhakrishnan Madhu, Sri Venkata Rao, Paturi Vishnupriya Das, Ashok Kumar Kaur, Tanvir Shukla, Deepak Kumar Mohan, Viswanathan Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study |
title | Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study |
title_full | Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study |
title_fullStr | Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study |
title_full_unstemmed | Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study |
title_short | Prevalence of Dyslipidemia in Urban and Rural India: The ICMR–INDIAB Study |
title_sort | prevalence of dyslipidemia in urban and rural india: the icmr–indiab study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016101/ https://www.ncbi.nlm.nih.gov/pubmed/24817067 http://dx.doi.org/10.1371/journal.pone.0096808 |
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