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An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage

Circulating tumor DNA (ctDNA) represents a promising biomarker for noninvasive assessment of cancer burden, but existing methods have insufficient sensitivity or patient coverage for broad clinical applicability. Here we introduce CAncer Personalized Profiling by deep Sequencing (CAPP-Seq), an econo...

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Detalles Bibliográficos
Autores principales:	Newman, Aaron M., Bratman, Scott V., To, Jacqueline, Wynne, Jacob F., Eclov, Neville C. W., Modlin, Leslie A., Liu, Chih Long, Neal, Joel W., Wakelee, Heather A., Merritt, Robert E., Shrager, Joseph B., Loo, Billy W., Alizadeh, Ash A., Diehn, Maximilian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016134/ https://www.ncbi.nlm.nih.gov/pubmed/24705333 http://dx.doi.org/10.1038/nm.3519

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