Cargando…

A Stochastic Model Correctly Predicts Changes in Budding Yeast Cell Cycle Dynamics upon Periodic Expression of CLN2

In this study, we focus on a recent stochastic budding yeast cell cycle model. First, we estimate the model parameters using extensive data sets: phenotypes of 110 genetic strains, single cell statistics of wild type and cln3 strains. Optimization of stochastic model parameters is achieved by an aut...

Descripción completa

Detalles Bibliográficos
Autores principales: Oguz, Cihan, Palmisano, Alida, Laomettachit, Teeraphan, Watson, Layne T., Baumann, William T., Tyson, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016136/
https://www.ncbi.nlm.nih.gov/pubmed/24816736
http://dx.doi.org/10.1371/journal.pone.0096726