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Correlation of Nav1.8 and Nav1.9 sodium channel expression with neuropathic pain in human subjects with lingual nerve neuromas

BACKGROUND: Voltage-gated sodium channels Nav1.8 and Nav1.9 are expressed preferentially in small diameter sensory neurons, and are thought to play a role in the generation of ectopic activity in neuronal cell bodies and/or their axons following peripheral nerve injury. The expression of Nav1.8 and...

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Detalles Bibliográficos
Autores principales: Bird, Emma V, Christmas, Claire R, Loescher, Alison R, Smith, Keith G, Robinson, Peter P, Black, Joel A, Waxman, Stephen G, Boissonade, Fiona M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016210/
https://www.ncbi.nlm.nih.gov/pubmed/24144460
http://dx.doi.org/10.1186/1744-8069-9-52