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An objective function exploiting suboptimal solutions in metabolic networks
BACKGROUND: Flux Balance Analysis is a theoretically elegant, computationally efficient, genome-scale approach to predicting biochemical reaction fluxes. Yet FBA models exhibit persistent mathematical degeneracy that generally limits their predictive power. RESULTS: We propose a novel objective func...
Autores principales: | Wintermute, Edwin H, Lieberman, Tami D, Silver, Pamela A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016239/ https://www.ncbi.nlm.nih.gov/pubmed/24088221 http://dx.doi.org/10.1186/1752-0509-7-98 |
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