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Comparing Screening Instruments to Predict Posttraumatic Stress Disorder

BACKGROUND: Following traumatic exposure, a proportion of trauma victims develops posttraumatic stress disorder (PTSD). Early PTSD risk screening requires sensitive instruments to identify everyone at risk for developing PTSD in need of diagnostic follow-up. AIMS: This study compares the accuracy of...

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Autores principales: Mouthaan, Joanne, Sijbrandij, Marit, Reitsma, Johannes B., Gersons, Berthold P. R., Olff, Miranda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016271/
https://www.ncbi.nlm.nih.gov/pubmed/24816642
http://dx.doi.org/10.1371/journal.pone.0097183
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author Mouthaan, Joanne
Sijbrandij, Marit
Reitsma, Johannes B.
Gersons, Berthold P. R.
Olff, Miranda
author_facet Mouthaan, Joanne
Sijbrandij, Marit
Reitsma, Johannes B.
Gersons, Berthold P. R.
Olff, Miranda
author_sort Mouthaan, Joanne
collection PubMed
description BACKGROUND: Following traumatic exposure, a proportion of trauma victims develops posttraumatic stress disorder (PTSD). Early PTSD risk screening requires sensitive instruments to identify everyone at risk for developing PTSD in need of diagnostic follow-up. AIMS: This study compares the accuracy of the 4-item SPAN, 10-item Trauma Screening Questionnaire (TSQ) and 22-item Impact of Event Scale-Revised (IES-R) in predicting chronic PTSD at a minimum sensitivity of 80%. METHOD: Injury patients admitted to a level-I trauma centre (N = 311) completed the instruments at a median of 23 days and were clinically assessed for PTSD at 6 months. Areas under the curve and specificities at 80% sensitivity were compared between instruments. RESULTS: Areas under the curve in all instruments were adequate (SPAN: 0.83; TSQ: 0.82; IES-R: 0.83) with no significant differences. At 80% sensitivity, specificities were 64% for SPAN, 59% for TSQ and 72% for IES-R. CONCLUSION: The SPAN, TSQ and IES-R show similar accuracy in early detection of individuals at risk for PTSD, despite differences in number of items. The modest specificities and low positive predictive values found for all instruments could lead to relatively many false positive cases, when applied in clinical practice.
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spelling pubmed-40162712014-05-14 Comparing Screening Instruments to Predict Posttraumatic Stress Disorder Mouthaan, Joanne Sijbrandij, Marit Reitsma, Johannes B. Gersons, Berthold P. R. Olff, Miranda PLoS One Research Article BACKGROUND: Following traumatic exposure, a proportion of trauma victims develops posttraumatic stress disorder (PTSD). Early PTSD risk screening requires sensitive instruments to identify everyone at risk for developing PTSD in need of diagnostic follow-up. AIMS: This study compares the accuracy of the 4-item SPAN, 10-item Trauma Screening Questionnaire (TSQ) and 22-item Impact of Event Scale-Revised (IES-R) in predicting chronic PTSD at a minimum sensitivity of 80%. METHOD: Injury patients admitted to a level-I trauma centre (N = 311) completed the instruments at a median of 23 days and were clinically assessed for PTSD at 6 months. Areas under the curve and specificities at 80% sensitivity were compared between instruments. RESULTS: Areas under the curve in all instruments were adequate (SPAN: 0.83; TSQ: 0.82; IES-R: 0.83) with no significant differences. At 80% sensitivity, specificities were 64% for SPAN, 59% for TSQ and 72% for IES-R. CONCLUSION: The SPAN, TSQ and IES-R show similar accuracy in early detection of individuals at risk for PTSD, despite differences in number of items. The modest specificities and low positive predictive values found for all instruments could lead to relatively many false positive cases, when applied in clinical practice. Public Library of Science 2014-05-09 /pmc/articles/PMC4016271/ /pubmed/24816642 http://dx.doi.org/10.1371/journal.pone.0097183 Text en © 2014 Mouthaan et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Mouthaan, Joanne
Sijbrandij, Marit
Reitsma, Johannes B.
Gersons, Berthold P. R.
Olff, Miranda
Comparing Screening Instruments to Predict Posttraumatic Stress Disorder
title Comparing Screening Instruments to Predict Posttraumatic Stress Disorder
title_full Comparing Screening Instruments to Predict Posttraumatic Stress Disorder
title_fullStr Comparing Screening Instruments to Predict Posttraumatic Stress Disorder
title_full_unstemmed Comparing Screening Instruments to Predict Posttraumatic Stress Disorder
title_short Comparing Screening Instruments to Predict Posttraumatic Stress Disorder
title_sort comparing screening instruments to predict posttraumatic stress disorder
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016271/
https://www.ncbi.nlm.nih.gov/pubmed/24816642
http://dx.doi.org/10.1371/journal.pone.0097183
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