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Association of candidate single nucleotide polymorphisms with somatic mutation of the epidermal growth factor receptor pathway
BACKGROUND: Tumour growth in colorectal cancer and other solid cancers is frequently supported by activating mutations in the epidermal growth factor receptor (EGFR) signaling pathway (Patholog Res Int 2011:932932, 2011). Treatment of metastatic colorectal cancer with targeted anti-EGFR therapeutics...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016273/ https://www.ncbi.nlm.nih.gov/pubmed/24152305 http://dx.doi.org/10.1186/1755-8794-6-43 |