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An Optimized Triple Modality Reporter for Quantitative In Vivo Tumor Imaging and Therapy Evaluation

We present an optimized triple modality reporter construct combining a far-red fluorescent protein (E2-Crimson), enhanced firefly luciferase enzyme (Luc2), and truncated wild type herpes simplex virus I thymidine kinase (wttk) that allows for sensitive, long-term tracking of tumor growth in vivo by...

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Detalles Bibliográficos
Autores principales:	Levin, Rachel A., Felsen, Csilla N., Yang, Jin, Lin, John Y., Whitney, Michael A., Nguyen, Quyen T., Tsien, Roger Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016317/ https://www.ncbi.nlm.nih.gov/pubmed/24816650 http://dx.doi.org/10.1371/journal.pone.0097415

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