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Eribulin mesylate exerts specific gene expression changes in pericytes and shortens pericyte-driven capillary network in vitro
BACKGROUND: Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B. Eribulin is a tubulin-binding drug and approved in many countries worldwide for treatment of certain patients with advanced breast cancer. Here we investigated antiproliferativ...
Autores principales: | Agoulnik, Sergei I, Kawano, Satoshi, Taylor, Noel, Oestreicher, Judith, Matsui, Junji, Chow, Jesse, Oda, Yoshiya, Funahashi, Yasuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016419/ https://www.ncbi.nlm.nih.gov/pubmed/24581301 http://dx.doi.org/10.1186/2045-824X-6-3 |
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