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Clock gene Bmal1 is dispensable for intrinsic properties of murine hematopoietic stem cells

BACKGROUND: Circadian rhythms are known to influence a variety of biological phenomena such as cell cycle, sleep-wake rhythm, hormone release and other important physiological functions. Given that cell cycle entry of hibernating hematopoietic stem cells (HSCs) plays a critical role in controlling h...

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Detalles Bibliográficos
Autores principales: Ieyasu, Aki, Tajima, Yoko, Shimba, Shigeki, Nakauchi, Hiromitsu, Yamazaki, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016489/
https://www.ncbi.nlm.nih.gov/pubmed/24606809
http://dx.doi.org/10.1186/1477-5751-13-4