Cargando…

Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model

BACKGROUND: Non-cell-autonomous motor neuronal death is suggested in a mutant Cu/Zn superoxide dismutase 1 (mSOD1)-mediated amyotrophic lateral sclerosis (ALS) model, in which glial cells play significant roles in disease progression. Connexins (Cxs) form homotypic or heterotypic gap junctions (GJs)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Yiwen, Masaki, Katsuhisa, Yamasaki, Ryo, Imamura, Shihoko, Suzuki, Satoshi O, Hayashi, Shintaro, Sato, Shinya, Nagara, Yuko, Kawamura, Mami F, Kira, Jun-ichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016493/ https://www.ncbi.nlm.nih.gov/pubmed/24597481 http://dx.doi.org/10.1186/1742-2094-11-42

Ejemplares similares

Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis
por: Kobayakawa, Yuko, et al.
Publicado: (2018)

Connexin 43 Astrocytopathy Linked to Rapidly Progressive Multiple Sclerosis and Neuromyelitis Optica
por: Masaki, Katsuhisa, et al.
Publicado: (2013)

Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
por: Watanabe, Mitsuru, et al.
Publicado: (2016)

Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
por: Une, Hayato, et al.
Publicado: (2021)

Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation
por: Hashimoto, Yu, et al.
Publicado: (2022)

Connexin 30 Deficiency Attenuates Chronic but Not Acute Phases of Experimental Autoimmune Encephalomyelitis Through Induction of Neuroprotective Microglia
por: Fang, Mei, et al.
Publicado: (2018)

Connexin 30 deficiency attenuates A2 astrocyte responses and induces severe neurodegeneration in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride Parkinson’s disease animal model
por: Fujita, Atsushi, et al.
Publicado: (2018)

Connexin 43/47 channels are important for astrocyte/oligodendrocyte cross-talk in myelination and demyelination
por: Basu, Rahul, et al.
Publicado: (2018)

Serum Anti-oligodendrocyte Autoantibodies in Patients With Multiple Sclerosis Detected by a Tissue-Based Immunofluorescence Assay
por: Miyachi, Yukino, et al.
Publicado: (2021)

Dysregulation of Astrocytic HMGB1 Signaling in Amyotrophic Lateral Sclerosis
por: Brambilla, Liliana, et al.
Publicado: (2018)

Connexins in Astrocyte Migration
por: Lagos-Cabré, Raúl, et al.
Publicado: (2020)

Inhibition of Astrocyte Connexin 43 Channels Facilitates the Differentiation of Oligodendrocyte Precursor Cells Under Hypoxic Conditions In Vitro
por: Wang, Qiong, et al.
Publicado: (2018)

Early and extensive alterations of glial connexins, distal oligodendrogliopathy type demyelination, and nodal/paranodal pathology are characteristic of multiple system atrophy
por: Nishimura, Yuji, et al.
Publicado: (2022)

Dysfunction of the oligodendrocytes in amyotrophic lateral sclerosis
por: Gong, Zhenxiang, et al.
Publicado: (2022)

Astrocyte–Oligodendrocyte–Microglia Crosstalk in Astrocytopathies
por: de Waard, Dieuwke Maria, et al.
Publicado: (2020)

Novel disease-modifying anti-rheumatic drug iguratimod suppresses chronic experimental autoimmune encephalomyelitis by down-regulating activation of macrophages/microglia through an NF-κB pathway
por: Li, Guangrui, et al.
Publicado: (2018)

Fluoxetin Upregulates Connexin 43 Expression in Astrocyte
por: Mostafavi, Hossein, et al.
Publicado: (2014)

Connexin 43 Controls the Astrocyte Immunoregulatory Phenotype
por: Boulay, Anne-Cécile, et al.
Publicado: (2018)

Connexin Hemichannels in Astrocytes: Role in CNS Disorders
por: Xing, LingYan, et al.
Publicado: (2019)

Connexin and Pannexin-Based Channels in Oligodendrocytes: Implications in Brain Health and Disease
por: Vejar, Sebastián, et al.
Publicado: (2019)

Peripheral Blood T Cell Dynamics Predict Relapse in Multiple Sclerosis Patients on Fingolimod
por: Song, Zi-Ye, et al.
Publicado: (2015)

Metabolic Aspects of Neuron-Oligodendrocyte-Astrocyte Interactions
por: Amaral, Ana I., et al.
Publicado: (2013)

Osmotic Demyelination: From an Oligodendrocyte to an Astrocyte Perspective
por: Nicaise, Charles, et al.
Publicado: (2019)

Developmental Origins of Human Cortical Oligodendrocytes and Astrocytes
por: Yang, Lin, et al.
Publicado: (2021)

Differentiation of Oligodendrocyte Precursor Cells from Sox10-Venus Mice to Oligodendrocytes and Astrocytes
por: Suzuki, Nobuharu, et al.
Publicado: (2017)

Antidepressants Impact Connexin 43 Channel Functions in Astrocytes
por: Jeanson, Tiffany, et al.
Publicado: (2016)

Oligodendrocyte Dysfunction in Amyotrophic Lateral Sclerosis: Mechanisms and Therapeutic Perspectives
por: Raffaele, Stefano, et al.
Publicado: (2021)

Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology
por: Li, Jiasi, et al.
Publicado: (2016)

Molecular Neuropathology of Astrocytes and Oligodendrocytes in Alcohol Use Disorders
por: Miguel-Hidalgo, José J.
Publicado: (2018)

Iron Metabolism in Oligodendrocytes and Astrocytes, Implications for Myelination and Remyelination
por: Cheli, Veronica T., et al.
Publicado: (2020)

Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System
por: Nutma, Erik, et al.
Publicado: (2020)

EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes
por: Liu, Xinyu, et al.
Publicado: (2022)

Lymphocyte deficiency alters the transcriptomes of oligodendrocytes, but not astrocytes or microglia
por: Krawczyk, Mitchell C., et al.
Publicado: (2023)

Connexin-Mediated Functional and Metabolic Coupling Between Astrocytes and Neurons
por: Mayorquin, Lady C., et al.
Publicado: (2018)

Astrocytic Connexin43 Channels as Candidate Targets in Epilepsy Treatment
por: Walrave, Laura, et al.
Publicado: (2020)

Association of Decreased Percentage of Vδ2(+)Vγ9(+) γδ T Cells With Disease Severity in Multiple Sclerosis
por: Maimaitijiang, Guzailiayi, et al.
Publicado: (2018)

Connexin 30 Expression and Frequency of Connexin Heterogeneity in Astrocyte Gap Junction Plaques Increase with Age in the Rat Retina
por: Mansour, Hussein, et al.
Publicado: (2013)

RNA Dysregulation in Amyotrophic Lateral Sclerosis
por: Butti, Zoe, et al.
Publicado: (2019)

Dysregulation of Connexin Expression Plays a Pivotal Role in Psoriasis
por: O’Shaughnessy, Erin M., et al.
Publicado: (2021)

Dysregulation of Iron Metabolism in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis
por: Oshiro, Satoru, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_79eumo8a4nbtkeo6qk4hugdlm3