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Genetically engineered endostatin-lidamycin fusion proteins effectively inhibit tumor growth and metastasis

BACKGROUND: Endostatin (ES) inhibits endothelial cell proliferation, migration, invasion, and tube formation. It also shows antiangiogenesis and antitumor activities in several animal models. Endostatin specifically targets tumor vasculature to block tumor growth. Lidamycin (LDM), which consists of...

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Detalles Bibliográficos
Autores principales:	Jiang, Wen-guo, Lu, Xin-an, Shang, Bo-yang, Fu, Yan, Zhang, Sheng-hua, Zhou, Daifu, Li, Liang, Li, Yi, Luo, Yongzhang, Zhen, Yong-su
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016579/ https://www.ncbi.nlm.nih.gov/pubmed/24128285 http://dx.doi.org/10.1186/1471-2407-13-479

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