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Is quality of life post cardiac surgery overestimated?
BACKGROUND: Quality of Life (QoL) studies concerns the difference in QoL between the baseline and the post-surgical assessment. Many such studies, however, suffer from incomplete QoL-data with regard to patients with a proven survival - the drop-outs. Our hypothesis is that patients with a low preop...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016622/ https://www.ncbi.nlm.nih.gov/pubmed/24773766 http://dx.doi.org/10.1186/1477-7525-12-62 |
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author | Noyez, Luc |
author_facet | Noyez, Luc |
author_sort | Noyez, Luc |
collection | PubMed |
description | BACKGROUND: Quality of Life (QoL) studies concerns the difference in QoL between the baseline and the post-surgical assessment. Many such studies, however, suffer from incomplete QoL-data with regard to patients with a proven survival - the drop-outs. Our hypothesis is that patients with a low preoperative QoL, high operative risk and older age are at higher risk for drop-out, which may result in a biased conclusion. METHODS: This study includes 1675 patients, all of whom were operated between July 1, 2009 and July 1,2012 and have a proven one-year survival, as well as a complete preoperative EuroQoL registration (EQ-5D and EQ-VAS). Based on the calculated 30 and 70 percentiles of age, EuroSCORE risk, and EQ-5D and EQ-VAS values, the group was split into three different subgroups. We studied whether (1) there was a correlation between age, risk, preoperative QoL and postoperative QoL and (2) if the drop-outs were correlated to age, risk and preoperative QoL. RESULTS: There is a statistically significant correlation between postoperative QoL and both age (p = 0.029) and risk (p = 0.002). Both relations have a negative Pearson’s r. There is also a statistically significant (p = 0.0001) correlation between pre- and postoperative QoL, now with a positive Pearson’s r. The percentage of drop-outs increases in a statistically significant manner with an increased risk (p = 0.001), older age (p = 0.001) and a low preoperative QoL (EQ-5D, p = 0.001 and EQ-VAS, p = 0.003). CONCLUSION: We conclude that QoL post cardiac surgery is overestimated, certainly for older, high risk patients and patients with a low preoperative QoL. |
format | Online Article Text |
id | pubmed-4016622 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-40166222014-05-11 Is quality of life post cardiac surgery overestimated? Noyez, Luc Health Qual Life Outcomes Research BACKGROUND: Quality of Life (QoL) studies concerns the difference in QoL between the baseline and the post-surgical assessment. Many such studies, however, suffer from incomplete QoL-data with regard to patients with a proven survival - the drop-outs. Our hypothesis is that patients with a low preoperative QoL, high operative risk and older age are at higher risk for drop-out, which may result in a biased conclusion. METHODS: This study includes 1675 patients, all of whom were operated between July 1, 2009 and July 1,2012 and have a proven one-year survival, as well as a complete preoperative EuroQoL registration (EQ-5D and EQ-VAS). Based on the calculated 30 and 70 percentiles of age, EuroSCORE risk, and EQ-5D and EQ-VAS values, the group was split into three different subgroups. We studied whether (1) there was a correlation between age, risk, preoperative QoL and postoperative QoL and (2) if the drop-outs were correlated to age, risk and preoperative QoL. RESULTS: There is a statistically significant correlation between postoperative QoL and both age (p = 0.029) and risk (p = 0.002). Both relations have a negative Pearson’s r. There is also a statistically significant (p = 0.0001) correlation between pre- and postoperative QoL, now with a positive Pearson’s r. The percentage of drop-outs increases in a statistically significant manner with an increased risk (p = 0.001), older age (p = 0.001) and a low preoperative QoL (EQ-5D, p = 0.001 and EQ-VAS, p = 0.003). CONCLUSION: We conclude that QoL post cardiac surgery is overestimated, certainly for older, high risk patients and patients with a low preoperative QoL. BioMed Central 2014-04-29 /pmc/articles/PMC4016622/ /pubmed/24773766 http://dx.doi.org/10.1186/1477-7525-12-62 Text en Copyright © 2014 Noyez; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Noyez, Luc Is quality of life post cardiac surgery overestimated? |
title | Is quality of life post cardiac surgery overestimated? |
title_full | Is quality of life post cardiac surgery overestimated? |
title_fullStr | Is quality of life post cardiac surgery overestimated? |
title_full_unstemmed | Is quality of life post cardiac surgery overestimated? |
title_short | Is quality of life post cardiac surgery overestimated? |
title_sort | is quality of life post cardiac surgery overestimated? |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016622/ https://www.ncbi.nlm.nih.gov/pubmed/24773766 http://dx.doi.org/10.1186/1477-7525-12-62 |
work_keys_str_mv | AT noyezluc isqualityoflifepostcardiacsurgeryoverestimated |