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Synthesis and biological evaluation of glucagon-like peptide-1 receptor agonists
In this study, a series of fused-heterocyclic derivatives were systematically designed and synthesized using an efficient route, and evaluated in terms of GLP-1R agonist activity. We employed short synthetic steps and reactions that are tolerant of the presence of various functional groups and suita...
Autores principales: | Zhang, Yu-Juan, Shen, Liu-Lan, Cheon, Hyae-Gyeong, Xu, Yong-Nan, Jeong, Jin-Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pharmaceutical Society of Korea
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016675/ https://www.ncbi.nlm.nih.gov/pubmed/24178744 http://dx.doi.org/10.1007/s12272-013-0253-9 |
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