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Reference-free cell mixture adjustments in analysis of DNA methylation data
Motivation: Recently there has been increasing interest in the effects of cell mixture on the measurement of DNA methylation, specifically the extent to which small perturbations in cell mixture proportions can register as changes in DNA methylation. A recently published set of statistical methods e...
Autores principales: | Houseman, Eugene Andres, Molitor, John, Marsit, Carmen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016702/ https://www.ncbi.nlm.nih.gov/pubmed/24451622 http://dx.doi.org/10.1093/bioinformatics/btu029 |
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