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siRNA delivery targeting to the lung via agglutination-induced accumulation and clearance of cationic tetraamino fullerene
The efficient treatment of lung diseases requires lung-selective delivery of agents to the lung. However, lung-selective delivery is difficult because the accumulation of micrometer-sized carriers in the lung often induces inflammation and embolization-related toxicity. Here we demonstrate a lung-se...
Autores principales: | MINAMI, Kosuke, OKAMOTO, Koji, DOI, Kent, HARANO, Koji, NOIRI, Eisei, NAKAMURA, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017229/ https://www.ncbi.nlm.nih.gov/pubmed/24814863 http://dx.doi.org/10.1038/srep04916 |
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