Chronic constipation: no more idiopathic, but a true neuropathological entity

Chronic constipation is still considered a functional or idiopathic disorder. However, in recent years there is evidence that its pathopysiological grounds may be actually due to a complex system of abnormalities of the enteric nervous system of these patients. In particular, as reported in this rev...

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Autores principales: Bassotti, Gabrio, Villanacci, Vincenzo, Nejad, Mohammad Rostami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Institute for Gastroenterology and Liver Diseases 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017417/
https://www.ncbi.nlm.nih.gov/pubmed/24834167
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author Bassotti, Gabrio
Villanacci, Vincenzo
Nejad, Mohammad Rostami
author_facet Bassotti, Gabrio
Villanacci, Vincenzo
Nejad, Mohammad Rostami
author_sort Bassotti, Gabrio
collection PubMed
description Chronic constipation is still considered a functional or idiopathic disorder. However, in recent years there is evidence that its pathopysiological grounds may be actually due to a complex system of abnormalities of the enteric nervous system of these patients. In particular, as reported in this review, the enteric glial cells seem to be constantly involved in constipated patients, suggesting that (at least some forms of) constipation should be considered as true neuro-gliopathies.
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spelling pubmed-40174172014-05-15 Chronic constipation: no more idiopathic, but a true neuropathological entity Bassotti, Gabrio Villanacci, Vincenzo Nejad, Mohammad Rostami Gastroenterol Hepatol Bed Bench Review Article Chronic constipation is still considered a functional or idiopathic disorder. However, in recent years there is evidence that its pathopysiological grounds may be actually due to a complex system of abnormalities of the enteric nervous system of these patients. In particular, as reported in this review, the enteric glial cells seem to be constantly involved in constipated patients, suggesting that (at least some forms of) constipation should be considered as true neuro-gliopathies. Research Institute for Gastroenterology and Liver Diseases 2011 /pmc/articles/PMC4017417/ /pubmed/24834167 Text en Copyright © 2011 Research Institute for Gastroenterology and Liver Diseases http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Review Article
Bassotti, Gabrio
Villanacci, Vincenzo
Nejad, Mohammad Rostami
Chronic constipation: no more idiopathic, but a true neuropathological entity
title Chronic constipation: no more idiopathic, but a true neuropathological entity
title_full Chronic constipation: no more idiopathic, but a true neuropathological entity
title_fullStr Chronic constipation: no more idiopathic, but a true neuropathological entity
title_full_unstemmed Chronic constipation: no more idiopathic, but a true neuropathological entity
title_short Chronic constipation: no more idiopathic, but a true neuropathological entity
title_sort chronic constipation: no more idiopathic, but a true neuropathological entity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017417/
https://www.ncbi.nlm.nih.gov/pubmed/24834167
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AT villanaccivincenzo chronicconstipationnomoreidiopathicbutatrueneuropathologicalentity
AT nejadmohammadrostami chronicconstipationnomoreidiopathicbutatrueneuropathologicalentity

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