The concentration of serum zinc in celiac patients compared to healthy subjects in Tehran

AIM: This study evaluated serum levels of zinc in patient with CD compare to healthy subjects. BACKGROUND: Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biologica...

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Detalles Bibliográficos
Autores principales: Fathi, Fariba, Ektefa, Fatemeh, Tafazzoli, Mohsen, Rostami, Kamran, Nejad, Mohammad Rostami, Fathi, Mohsen, Rezaei-Tavirani, Mostafa, Oskouie, Afsaneh Arefi, Zali, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Institute for Gastroenterology and Liver Diseases 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017501/
https://www.ncbi.nlm.nih.gov/pubmed/24834251
Descripción
Sumario:AIM: This study evaluated serum levels of zinc in patient with CD compare to healthy subjects. BACKGROUND: Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biological functions. PATIENTS AND METHODS: Sera of 30 celiac cases and 30 healthy normal cohorts as control group were obtained. Atomic absorption spectrophotometer was employed for estimating serum zinc level. RESULTS: Zinc concentrations in patients diagnosed with CD were significantly lower than healthy subjects (75.97±12 compared with 92.83±18, P-value < 0.0001). CONCLUSION: The result of this study shows that serum zinc concentration is decreased in celiac patients compare to healthy controls. Serum zinc may thus be a marker of CD in adults presenting with gastrointestinal symptoms.

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