The CpG island methylator phenotype (CIMP) in colorectal cancer

It is clear that colorectal cancer (CRC) develops through multiple genetic and epigenetic pathways. These pathways may be determined on the basis of three molecular features: (i) mutations in DNA mismatch repair genes, leading to a DNA microsatellite instability (MSI) phenotype, (ii) mutations in AP...

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Detalles Bibliográficos
Autores principales: Mojarad, Ehsan Nazemalhosseini, Kuppen, Peter JK, Aghdaei, Hamid Asadzadeh, Zali, Mohammad Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Institute for Gastroenterology and Liver Diseases 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017514/
https://www.ncbi.nlm.nih.gov/pubmed/24834258

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