Development and function of human innate immune cells in a humanized mouse model

Mice repopulated with human hematopoietic cells are a powerful tool for the study of human hematopoiesis and immune function in vivo. However, existing humanized mouse models are unable to support development of human innate immune cells, including myeloid cells and NK cells. Here we describe a mous...

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Detalles Bibliográficos
Autores principales: Rongvaux, Anthony, Willinger, Tim, Martinek, Jan, Strowig, Till, Gearty, Sofia V., Teichmann, Lino L., Saito, Yasuyuki, Marches, Florentina, Halene, Stephanie, Palucka, A. Karolina, Manz, Markus G., Flavell, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017589/
https://www.ncbi.nlm.nih.gov/pubmed/24633240
http://dx.doi.org/10.1038/nbt.2858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017589/
https://www.ncbi.nlm.nih.gov/pubmed/24633240
http://dx.doi.org/10.1038/nbt.2858

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