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Development and function of human innate immune cells in a humanized mouse model
Mice repopulated with human hematopoietic cells are a powerful tool for the study of human hematopoiesis and immune function in vivo. However, existing humanized mouse models are unable to support development of human innate immune cells, including myeloid cells and NK cells. Here we describe a mous...
Autores principales: | Rongvaux, Anthony, Willinger, Tim, Martinek, Jan, Strowig, Till, Gearty, Sofia V., Teichmann, Lino L., Saito, Yasuyuki, Marches, Florentina, Halene, Stephanie, Palucka, A. Karolina, Manz, Markus G., Flavell, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017589/ https://www.ncbi.nlm.nih.gov/pubmed/24633240 http://dx.doi.org/10.1038/nbt.2858 |
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