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DNA Damage by Histone Radicals in Nucleosome Core Particles
[Image: see text] Although DNA binding proteins shield the genetic material from diffusible reactive oxygen species by reacting with them, the resulting protein (peroxyl) radicals can oxidize the bound DNA. To explore this possible DNA damage by protein radicals, histone H4 proteins containing an az...
Autores principales: | Zhou, Chuanzheng, Greenberg, Marc M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017609/ https://www.ncbi.nlm.nih.gov/pubmed/24754228 http://dx.doi.org/10.1021/ja501285s |
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