Genetic interactions affecting human gene expression identified by variance association mapping

Non-additive interaction between genetic variants, or epistasis, is a possible explanation for the gap between heritability of complex traits and the variation explained by identified genetic loci. Interactions give rise to genotype dependent variance, and therefore the identification of variance qu...

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Detalles Bibliográficos
Autores principales: Brown, Andrew Anand, Buil, Alfonso, Viñuela, Ana, Lappalainen, Tuuli, Zheng, Hou-Feng, Richards, J Brent, Small, Kerrin S, Spector, Timothy D, Dermitzakis, Emmanouil T, Durbin, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017648/
https://www.ncbi.nlm.nih.gov/pubmed/24771767
http://dx.doi.org/10.7554/eLife.01381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017648/
https://www.ncbi.nlm.nih.gov/pubmed/24771767
http://dx.doi.org/10.7554/eLife.01381

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