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The E3 Ligase CHIP: Insights into Its Structure and Regulation
The carboxy-terminus of Hsc70 interacting protein (CHIP) is a cochaperone E3 ligase containing three tandem repeats of tetratricopeptide (TPR) motifs and a C-terminal U-box domain separated by a charged coiled-coil region. CHIP is known to function as a central quality control E3 ligase and regulate...
Autores principales: | Paul, Indranil, Ghosh, Mrinal K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017836/ https://www.ncbi.nlm.nih.gov/pubmed/24868554 http://dx.doi.org/10.1155/2014/918183 |
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