Cargando…

The E3 Ligase CHIP: Insights into Its Structure and Regulation

The carboxy-terminus of Hsc70 interacting protein (CHIP) is a cochaperone E3 ligase containing three tandem repeats of tetratricopeptide (TPR) motifs and a C-terminal U-box domain separated by a charged coiled-coil region. CHIP is known to function as a central quality control E3 ligase and regulate...

Descripción completa

Detalles Bibliográficos
Autores principales: Paul, Indranil, Ghosh, Mrinal K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017836/
https://www.ncbi.nlm.nih.gov/pubmed/24868554
http://dx.doi.org/10.1155/2014/918183

Ejemplares similares