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Efficacy of PolyMPC–DOX Prodrugs in 4T1 Tumor-Bearing Mice

[Image: see text] We report the in vivo efficacy, in tumor-bearing mice, of cancer prodrugs consisting of poly(methacryloyloxyethyl phosphorylcholine) (polyMPC) conjugated to doxorubicin (DOX). Our synthesis of polyMPC–DOX conjugates established prodrugs with tunable drug loading, pH sensitive relea...

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Detalles Bibliográficos
Autores principales:	McRae Page, Samantha, Henchey, Elizabeth, Chen, Xiangji, Schneider, Sallie, Emrick, Todd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018119/ https://www.ncbi.nlm.nih.gov/pubmed/24750072 http://dx.doi.org/10.1021/mp500009r

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