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Palladium Hydride Promoted Stereoselective Isomerization of Unactivated Di(exo)methylenes to Endocyclic Dienes
[Image: see text] The exomethylenes of 2,6-disubstituted bicyclo[3.3.1]nonan-9-ones 2 are readily isomerized over a palladium catalyst under an atmosphere of hydrogen to predominantly form the isomer 3 with C(2) symmetry with very little formation of the analogous product with C(s) symmetry. A hydro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018140/ https://www.ncbi.nlm.nih.gov/pubmed/24720691 http://dx.doi.org/10.1021/ol500710v |
| _version_ | 1782480031363104768 |
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| author | Jung, Michael E. Lee, Gloria S. Pham, Hung V. Houk, K. N. |
| author_facet | Jung, Michael E. Lee, Gloria S. Pham, Hung V. Houk, K. N. |
| author_sort | Jung, Michael E. |
| collection | PubMed |
| description | [Image: see text] The exomethylenes of 2,6-disubstituted bicyclo[3.3.1]nonan-9-ones 2 are readily isomerized over a palladium catalyst under an atmosphere of hydrogen to predominantly form the isomer 3 with C(2) symmetry with very little formation of the analogous product with C(s) symmetry. A hydrogen source is essential to effect the rearrangement. |
| format | Online Article Text |
| id | pubmed-4018140 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | American
Chemical Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-40181402015-04-11 Palladium Hydride Promoted Stereoselective Isomerization of Unactivated Di(exo)methylenes to Endocyclic Dienes Jung, Michael E. Lee, Gloria S. Pham, Hung V. Houk, K. N. Org Lett [Image: see text] The exomethylenes of 2,6-disubstituted bicyclo[3.3.1]nonan-9-ones 2 are readily isomerized over a palladium catalyst under an atmosphere of hydrogen to predominantly form the isomer 3 with C(2) symmetry with very little formation of the analogous product with C(s) symmetry. A hydrogen source is essential to effect the rearrangement. American Chemical Society 2014-04-11 2014-05-02 /pmc/articles/PMC4018140/ /pubmed/24720691 http://dx.doi.org/10.1021/ol500710v Text en Copyright © 2014 American Chemical Society |
| spellingShingle | Jung, Michael E. Lee, Gloria S. Pham, Hung V. Houk, K. N. Palladium Hydride Promoted Stereoselective Isomerization of Unactivated Di(exo)methylenes to Endocyclic Dienes |
| title | Palladium Hydride Promoted Stereoselective Isomerization
of Unactivated Di(exo)methylenes to Endocyclic Dienes |
| title_full | Palladium Hydride Promoted Stereoselective Isomerization
of Unactivated Di(exo)methylenes to Endocyclic Dienes |
| title_fullStr | Palladium Hydride Promoted Stereoselective Isomerization
of Unactivated Di(exo)methylenes to Endocyclic Dienes |
| title_full_unstemmed | Palladium Hydride Promoted Stereoselective Isomerization
of Unactivated Di(exo)methylenes to Endocyclic Dienes |
| title_short | Palladium Hydride Promoted Stereoselective Isomerization
of Unactivated Di(exo)methylenes to Endocyclic Dienes |
| title_sort | palladium hydride promoted stereoselective isomerization
of unactivated di(exo)methylenes to endocyclic dienes |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018140/ https://www.ncbi.nlm.nih.gov/pubmed/24720691 http://dx.doi.org/10.1021/ol500710v |
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