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Platelet-Derived Growth Factor Receptor-β Antagonism Restores Morphine Analgesic Potency against Neuropathic Pain

BACKGROUND: Chronic, intractable pain is a problem of pandemic proportions. Pain caused by nerve injuries (neuropathic pain) is extremely difficult to treat. For centuries, opiates such as morphine have been the first-line treatment for severe chronic pain. However, opiates are often ineffective aga...

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Detalles Bibliográficos
Autores principales: Donica, Courtney L., Cui, Yan, Shi, Shanping, Gutstein, Howard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018247/
https://www.ncbi.nlm.nih.gov/pubmed/24820332
http://dx.doi.org/10.1371/journal.pone.0097105