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Platelet-Derived Growth Factor Receptor-β Antagonism Restores Morphine Analgesic Potency against Neuropathic Pain
BACKGROUND: Chronic, intractable pain is a problem of pandemic proportions. Pain caused by nerve injuries (neuropathic pain) is extremely difficult to treat. For centuries, opiates such as morphine have been the first-line treatment for severe chronic pain. However, opiates are often ineffective aga...
Autores principales: | Donica, Courtney L., Cui, Yan, Shi, Shanping, Gutstein, Howard B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018247/ https://www.ncbi.nlm.nih.gov/pubmed/24820332 http://dx.doi.org/10.1371/journal.pone.0097105 |
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