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Regulation and Novel Action of Thymidine Phosphorylase in Non-Small Cell Lung Cancer: Crosstalk with Nrf2 and HO-1

Proangiogenic enzyme thymidine phosphorylase (TP) is a promising target for anticancer therapy, yet its action in non-small cell lung carcinoma (NSCLC) is not fully understood. To elucidate its role in NSCLC tumor growth, NCI-H292 lung mucoepidermoid carcinoma cells and endothelial cells were engine...

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Detalles Bibliográficos
Autores principales: Tertil, Magdalena, Skrzypek, Klaudia, Florczyk, Urszula, Weglarczyk, Kazimierz, Was, Halina, Collet, Guillaume, Guichard, Alan, Gil, Tomasz, Kuzdzal, Jaroslaw, Jozkowicz, Alicja, Kieda, Claudine, Pichon, Chantal, Dulak, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018251/
https://www.ncbi.nlm.nih.gov/pubmed/24819505
http://dx.doi.org/10.1371/journal.pone.0097070

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