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Contribution of Intestinal Barrier Damage, Microbial Translocation and HIV-1 Infection Status to an Inflammaging Signature

BACKGROUND: Systemic inflammation is a characteristic of both HIV-1 infection and aging (“inflammaging”). Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear. METHODS: Plasma biomarke...

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Detalles Bibliográficos
Autores principales: Steele, Amanda K., Lee, Eric J., Vestal, Brian, Hecht, Daniel, Dong, Zachary, Rapaport, Eric, Koeppe, John, Campbell, Thomas B., Wilson, Cara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018269/
https://www.ncbi.nlm.nih.gov/pubmed/24819230
http://dx.doi.org/10.1371/journal.pone.0097171